Social anxiety disorder (SAD) can feel overwhelming, affecting daily life and social interactions. Thankfully, researchers are constantly working on new treatments to help manage this condition. In this blog, we’ll explore some investigational drugs that are currently being studied for SAD.

What Are Investigational Drugs?

Investigational drugs are medications that are being tested for safety and efficacy but haven’t yet been approved for public use. These drugs often go through several phases of clinical trials before they can be made available to patients.

Types of Investigational Drugs for Social Anxiety Disorder

Here are some potential types of drugs that are being investigated:

1. Selective Serotonin Reuptake Inhibitors (SSRIs)

• Example: Fetzima (levomilnacipran)
• How it works: Increases serotonin levels in the brain, which can help improve mood and reduce anxiety.

2. Cognitive Behavioral Therapy) (CBT) Augmented Medications

• Example: D-cycloserine
• How it works: Enhances the effects of therapy, potentially making treatment more effective.

3. Beta-Blockers

• Example: Propranolol
• How it works: Reduces physical symptoms of anxiety like rapid heartbeat, helping individuals feel calmer in social situations.

4. Novel Compounds

• Example: Psilocybin
• How it works: Derived from mushrooms, this compound is showing promise in helping reduce anxiety by altering brain connectivity and emotional responses.

Comparison of Investigational Drugs

Real-Life Examples

• Fetzima: In clinical trials, participants reported lower levels of anxiety when taking this medication compared to a placebo. Many found it easier to engage in social situations.
• Propranolol: Often used for public speaking anxiety, many users say it helps them feel more relaxed and less jittery before speaking engagements.
• Psilocybin: In a recent study, individuals with social anxiety who received psilocybin reported significant reductions in anxiety and improved quality of life.

Steps to Consider Before Using These Drugs

1. Consult with a Healthcare Provider: Always talk to a healthcare professional before starting any investigational drug.
2. Understand the Risks: Be aware that these drugs are still in testing phases and may have unknown side effects.
3. Follow Clinical Trials: Look for clinical trials in your area that you may qualify for, as they can provide access to new treatments.
4. Monitor Your Progress: Keep track of how you feel and communicate this with your healthcare provider.

By staying informed about investigational drugs for social anxiety disorder, patients and their families can explore new options for treatment and support.